Treatment Overview

Over the past two decades, there has been considerable progress in the treatment of multiple sclerosis. There are now several therapeutic options available to patients. Your doctor will discuss these treatment options in detail and recommend treatments that are appropriate for your care. The following medications are available for patients:

Injectable Disease Modifying Therapies

Oral Disease Modifying Therapies

  • Gilenya (fingolimod)) – pill taken once a day
  • Tecfidera (dimethyl fumarate)  – pill taken twice a day
  • Aubagio (teriflunomide)– pill taken once a day
  • Mayzent (siponimod) – pill taken once daily
  • Mavenclad (cladribine) – pills taken as two treatment courses over 2 years. Each treatment course consists of 2 treatment weeks, one month apart

Infusion Disease Modifying Therapies

  • Tysabri (natalizumab) – Once a month infusion
  • Ocrevus (ocrelizumab) – Once every 6 months
  • Lemtrada (alemtuzumab) -5 infusion days – one year later 3 infusion days – additional infusions as needed


For Management of Acute Relapses


  • Intravenous methylprednisolone (Solumedrol) is used to treat relapses or exacerbations. It is given for 3 to 7 days with the premise that treatment decreases the duration and severity of the present attack.
  • Intravenous methylprednisolone may be given on a once monthly basis as an addition to a baseline medication.